Active Helicobacter pylori Infection Is a Risk Factor for Colorectal Mucosa: Early and Advanced Colonic Neoplasm Sequence
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Helicobacter pylori Infection with Atrophic Gastritis Is an Independent Risk Factor for Advanced Colonic Neoplasm
Background/Aims Helicobacter pylori is a major risk factor for atrophic gastritis (AG) and gastric cancer. The correlation between H. pylori, AG and colorectal neoplasm (CRN) has only been examined in a limited number of studies, and findings have been inconclusive. We aimed to investigate the association between H. pylori infection status, AG and advanced CRN. Methods This cross-sectional st...
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Colonic carcinogenesis is believed to be multifactorial process. In addition to hereditary and genetic factors, environmental factors such as Westernized dietary practice, smoking and alcohol consumption had also been contributed to increase the risk of colorectal cancer. 1 There has been growing interest in the relationship between infectious agents and colonic carcinogenesis. Especially, Heli...
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Background and objective: Helicobacter pylori infection is one of the most common chronic bacterial infections in the world, especially in the developing countries. This bacterium is the cause of many diseases such as lymphoma, gastritis, peptic ulcers, and stomach cancer. According to recent reports, H. pylori infection can potentially increase the risk of colon cancer. The cu...
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1. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012. CA Cancer J Clin. 2012;62(1):10-29. 2. Sonnenberg A. Differences in the birth-cohort patterns of gastric cancer and peptic ulcer. Gut. 2010;59(6):736-743. 3. Susser M. Period effects, generation effects and age effects in peptic ulcer mortality. J Chronic Dis. 1982;35(1):29-40. 4. Zhao YS, Wang F, Chang D, Han B, You DY. Meta-analysis...
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Background: Helicobacter pylori is the cause of serious diseases including gastric cancer and gastric mucosa–associated lymphoid tissue lymphoma.50% of world population is infected by this microorganism and it -based on epidemiologic studies - is mainly acquired during childhood . there is not enough evidence about prevalence of this infection in children and its risk factors so encourage us to...
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